{"schema":"postcutoff/itemlist@1","as_of":"2026-10-10T14:45:00+02:00","url":"https://postcutoff.com/news/21/","md":"https://postcutoff.com/news/21/index.md","disclosure":{"written_by":"AI agents (Claude Opus 5.5 in Claude Code)","editor":"Adam Bicz","policy":"https://postcutoff.com/about/"},"license":null,"item_type":"Event","scope":"all","page":21,"pages":23,"total":1105,"per_page":50,"feed":"https://postcutoff.com/feed.xml","items":[{"id":"2024-12-04-gencast-ensemble-weather","url":"https://postcutoff.com/e/2024-12-04-gencast-ensemble-weather/","date":"2024-12-04","date_precision":"day","short_title":"GenCast: diffusion-based ensemble forecast beats ECMWF's ENS on 97% of targets","deck":null,"takeaway":"GenCast (Nature, Dec 2024) is a diffusion model producing probabilistic 15-day ensemble forecasts.","category":"science","category_label":"Science & math","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google DeepMind"]},{"id":"2024-11-25-model-context-protocol","url":"https://postcutoff.com/e/2024-11-25-model-context-protocol/","date":"2024-11-25","date_precision":"day","short_title":"Anthropic open-sources the Model Context Protocol (MCP)","deck":null,"takeaway":"Solved the N×M integration problem for agents and became core infrastructure of the agentic AI ecosystem.","category":"agents","category_label":"Agents","importance":5,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":3,"official":3,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Anthropic"]},{"id":"2024-11-20-alphaqubit-quantum-error-correction","url":"https://postcutoff.com/e/2024-11-20-alphaqubit-quantum-error-correction/","date":"2024-11-20","date_precision":"day","short_title":"AlphaQubit: neural decoder sets accuracy record for quantum error correction on Google's Sycamore","deck":null,"takeaway":"Better decoding lowers the overhead of fault-tolerant quantum computing.","category":"science","category_label":"Science & math","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google DeepMind","Google Quantum AI"]},{"id":"2024-10-22-claude-computer-use","url":"https://postcutoff.com/e/2024-10-22-claude-computer-use/","date":"2024-10-22","date_precision":"day","short_title":"Anthropic releases computer use for Claude 3.5 Sonnet","deck":null,"takeaway":"Launched GUI agents at the frontier; OpenAI's Operator and Google's Project Mariner followed within months.","category":"agents","category_label":"Agents","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Anthropic"]},{"id":"2024-10-11-amodei-machines-of-loving-grace","url":"https://postcutoff.com/e/2024-10-11-amodei-machines-of-loving-grace/","date":"2024-10-11","date_precision":"day","short_title":"Dario Amodei publishes \"Machines of Loving Grace\"","deck":"How powerful AI could compress a century of progress into a decade","takeaway":"'Country of geniuses in a datacenter' became standard vocabulary, and the essay began Amodei's essay series.","category":"policy-safety","category_label":"Policy & safety","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Anthropic"]},{"id":"2024-10-09-nobel-chemistry-alphafold","url":"https://postcutoff.com/e/2024-10-09-nobel-chemistry-alphafold/","date":"2024-10-09","date_precision":"day","short_title":"Nobel Prize in Chemistry for protein design and AlphaFold","deck":null,"takeaway":"Confirmed AI as a tool of first-rank scientific discovery, less than four years after AlphaFold 2.","category":"milestone","category_label":"Milestones","importance":5,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":3,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Royal Swedish Academy of Sciences","Google DeepMind","University of Washington"]},{"id":"2024-10-08-nobel-physics-hopfield-hinton","url":"https://postcutoff.com/e/2024-10-08-nobel-physics-hopfield-hinton/","date":"2024-10-08","date_precision":"day","short_title":"Nobel Prize in Physics awarded to John Hopfield and Geoffrey Hinton","deck":null,"takeaway":"Together with the Chemistry prize a day later, it marked unprecedented recognition of AI by science's most prestigious award.","category":"milestone","category_label":"Milestones","importance":5,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":3,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Royal Swedish Academy of Sciences"]},{"id":"2024-09-23-altman-the-intelligence-age","url":"https://postcutoff.com/e/2024-09-23-altman-the-intelligence-age/","date":"2024-09-23","date_precision":"day","short_title":"Sam Altman publishes \"The Intelligence Age\"","deck":"Superintelligence possibly 'in a few thousand days'","takeaway":"It began a series of Altman essays (Three Observations, The Gentle Singularity) that shaped how the industry described its own trajectory, leading to his July 2026 remark that 'we are now, like, in the singularity'.","category":"policy-safety","category_label":"Policy & safety","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":1,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["OpenAI"]},{"id":"2024-09-12-openai-o1","url":"https://postcutoff.com/e/2024-09-12-openai-o1/","date":"2024-09-12","date_precision":"day","short_title":"OpenAI o1: reasoning models trained with reinforcement learning","deck":null,"takeaway":"Opened the 'reasoning model' era and a new scaling axis (test-time compute); every major lab followed within months.","category":"model-release","category_label":"Model releases","importance":5,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["OpenAI"]},{"id":"2024-09-05-alphaproteo","url":"https://postcutoff.com/e/2024-09-05-alphaproteo/","date":"2024-09-05","date_precision":"day","short_title":"AlphaProteo designs high-affinity protein binders","deck":"Including the first AI-designed VEGF-A binder","takeaway":"High one-shot success rates cut the months of screening normally needed to find a binder.","category":"science","category_label":"Science & math","importance":3,"confidence":"medium","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":2,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google DeepMind"]},{"id":"2024-08-01-eu-ai-act","url":"https://postcutoff.com/e/2024-08-01-eu-ai-act/","date":"2024-08-01","date_precision":"day","short_title":"EU AI Act enters into force","deck":null,"takeaway":"The first binding horizontal AI regulation by a major jurisdiction, with extraterritorial effect on all labs serving the EU market.","category":"policy-safety","category_label":"Policy & safety","importance":5,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":3,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["European Union"]},{"id":"2024-07-25-alphaproof-imo-silver","url":"https://postcutoff.com/e/2024-07-25-alphaproof-imo-silver/","date":"2024-07-25","date_precision":"day","short_title":"AlphaProof and AlphaGeometry 2 reach IMO silver-medal standard","deck":null,"takeaway":"First AI to reach medal level at the IMO; a year later, natural-language LLMs reached gold.","category":"science","category_label":"Science & math","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":3,"official":3,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google DeepMind"]},{"id":"2024-07-23-llama-3-1-405b","url":"https://postcutoff.com/e/2024-07-23-llama-3-1-405b/","date":"2024-07-23","date_precision":"day","short_title":"Llama 3.1 405B: the first frontier-class open-weights model","deck":null,"takeaway":"Narrowed the open–closed gap to months; open frontier weights reshaped policy debates and enabled wide distillation.","category":"open-source","category_label":"Open source","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Meta"]},{"id":"2024-07-22-neuralgcm","url":"https://postcutoff.com/e/2024-07-22-neuralgcm/","date":"2024-07-22","date_precision":"day","short_title":"NeuralGCM: Google's hybrid physics-ML atmosphere model matches top weather forecasts and runs decades-long climate simulations","deck":null,"takeaway":"It showed that ML can reach climate modelling, not only weather forecasting, and made differentiable hybrid GCMs a serious research direction.","category":"science","category_label":"Science & math","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":3,"official":3,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google Research","ECMWF","MIT","Harvard"]},{"id":"2024-06-25-esm3-esmgfp","url":"https://postcutoff.com/e/2024-06-25-esm3-esmgfp/","date":"2024-06-25","date_precision":"day","short_title":"ESM3 generates esmGFP, a new fluorescent protein estimated at '500 million years of evolution' from nature","deck":null,"takeaway":"It showed language models producing functional proteins far outside the natural sequence space.","category":"science","category_label":"Science & math","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["EvolutionaryScale"]},{"id":"2024-06-20-claude-3-5-sonnet","url":"https://postcutoff.com/e/2024-06-20-claude-3-5-sonnet/","date":"2024-06-20","date_precision":"day","short_title":"Claude 3.5 Sonnet launches with Artifacts","deck":null,"takeaway":"Established Claude as the leading coding model, driving adoption in tools like Cursor and paving the way for coding agents.","category":"model-release","category_label":"Model releases","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Anthropic"]},{"id":"2024-06-04-aschenbrenner-situational-awareness","url":"https://postcutoff.com/e/2024-06-04-aschenbrenner-situational-awareness/","date":"2024-06-04","date_precision":"day","short_title":"Leopold Aschenbrenner publishes \"Situational Awareness: The Decade Ahead\"","deck":"AGI by 2027, trillion-dollar clusters and 'The Project'.","takeaway":"It shaped the vocabulary of 2024–2026 AI discourse ('counting the OOMs', 'trillion-dollar cluster', 'The Project') and influenced policymakers and investors.","category":"policy-safety","category_label":"Policy & safety","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":4,"official":3,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Situational Awareness"]},{"id":"2024-06-04-right-to-warn-letter","url":"https://postcutoff.com/e/2024-06-04-right-to-warn-letter/","date":"2024-06-04","date_precision":"day","short_title":"\"A Right to Warn about Advanced AI\"","deck":"Current and former OpenAI and DeepMind employees demand whistleblower protections","takeaway":"It set the template for employee-led collective statements at frontier labs, which culminated in the July 2026 'Pacing the Frontier' statement signed by more than 1,100 lab employees.","category":"policy-safety","category_label":"Policy & safety","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":1,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["OpenAI","Google DeepMind"]},{"id":"2024-05-21-seoul-ai-summit","url":"https://postcutoff.com/e/2024-05-21-seoul-ai-summit/","date":"2024-05-21","date_precision":"day","short_title":"AI Seoul Summit: Frontier AI Safety Commitments","deck":null,"takeaway":"Led most frontier labs to publish responsible scaling / frontier safety frameworks, a key voluntary governance mechanism.","category":"policy-safety","category_label":"Policy & safety","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["UK Government","Republic of Korea Government"]},{"id":"2024-05-17-leike-resigns-superalignment-disbanded","url":"https://postcutoff.com/e/2024-05-17-leike-resigns-superalignment-disbanded/","date":"2024-05-17","date_precision":"day","short_title":"Jan Leike resigns, saying OpenAI's safety culture 'has taken a backseat to shiny products'","deck":"Superalignment team dissolved","takeaway":"It was the defining 'safety researchers leave a frontier lab' moment of 2024.","category":"policy-safety","category_label":"Policy & safety","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":6,"official":4,"filed":"2026-09-29","updated":"2026-09-29","orgs":["OpenAI"]},{"id":"2024-05-13-gpt-4o","url":"https://postcutoff.com/e/2024-05-13-gpt-4o/","date":"2024-05-13","date_precision":"day","short_title":"OpenAI launches GPT-4o, a natively multimodal 'omni' model","deck":null,"takeaway":"Made natural voice interaction with AI mainstream and set the standard for omni-modal assistants.","category":"model-release","category_label":"Model releases","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["OpenAI"]},{"id":"2024-05-08-alphafold-3","url":"https://postcutoff.com/e/2024-05-08-alphafold-3/","date":"2024-05-08","date_precision":"day","short_title":"AlphaFold 3 predicts structures and interactions of all life's molecules","deck":null,"takeaway":"Moved AI structural biology from single proteins to the molecular interactions that matter for medicine.","category":"science","category_label":"Science & math","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":3,"official":3,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google DeepMind","Isomorphic Labs"]},{"id":"2024-04-18-llama-3","url":"https://postcutoff.com/e/2024-04-18-llama-3/","date":"2024-04-18","date_precision":"day","short_title":"Meta releases Llama 3 (8B, 70B)","deck":null,"takeaway":"Showed the benefit of training small models far past Chinchilla-optimal, and narrowed the open/closed gap.","category":"open-source","category_label":"Open source","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Meta"]},{"id":"2024-03-18-nvidia-blackwell","url":"https://postcutoff.com/e/2024-03-18-nvidia-blackwell/","date":"2024-03-18","date_precision":"day","short_title":"NVIDIA unveils the Blackwell GPU platform","deck":null,"takeaway":"Blackwell racks became the building block of 2025's gigawatt-scale AI datacenters.","category":"hardware-compute","category_label":"Chips & compute","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["NVIDIA"]},{"id":"2024-03-04-claude-3","url":"https://postcutoff.com/e/2024-03-04-claude-3/","date":"2024-03-04","date_precision":"day","short_title":"Anthropic launches the Claude 3 family (Opus, Sonnet, Haiku)","deck":null,"takeaway":"Ended GPT-4's year-long uncontested lead and established the Opus/Sonnet/Haiku naming used thereafter.","category":"model-release","category_label":"Model releases","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Anthropic"]},{"id":"2024-02-21-ai-avoids-tokamak-tearing-instabilities","url":"https://postcutoff.com/e/2024-02-21-ai-avoids-tokamak-tearing-instabilities/","date":"2024-02-21","date_precision":"day","short_title":"AI controller predicts and avoids tearing instabilities in the DIII-D fusion reactor","deck":null,"takeaway":"Instabilities that can damage reactors are a key obstacle to fusion power.","category":"science","category_label":"Science & math","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":2,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Princeton University","Princeton Plasma Physics Laboratory","General Atomics"]},{"id":"2024-02-15-sora","url":"https://postcutoff.com/e/2024-02-15-sora/","date":"2024-02-15","date_precision":"day","short_title":"OpenAI previews Sora, a text-to-video 'world simulator'","deck":null,"takeaway":"Reset expectations for AI video overnight and triggered a video-generation race (Veo, Kling, Runway Gen-3).","category":"media-generation","category_label":"Media generation","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["OpenAI"]},{"id":"2024-02-15-gemini-1-5","url":"https://postcutoff.com/e/2024-02-15-gemini-1-5/","date":"2024-02-15","date_precision":"day","short_title":"Gemini 1.5 Pro brings a 1-million-token context window","deck":null,"takeaway":"Made million-token context a practical reality and shifted how developers used LLMs (whole-document and whole-repo prompting).","category":"model-release","category_label":"Model releases","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google DeepMind"]},{"id":"2024-01-17-alphageometry","url":"https://postcutoff.com/e/2024-01-17-alphageometry/","date":"2024-01-17","date_precision":"day","short_title":"AlphaGeometry solves olympiad geometry near gold-medallist level without human demonstrations","deck":null,"takeaway":"It was a step towards the 2024 IMO silver and 2025 gold, and showed that synthetic data could replace scarce human proofs.","category":"science","category_label":"Science & math","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":3,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google DeepMind","New York University"]},{"id":"2024-01-09-microsoft-pnnl-battery-electrolyte","url":"https://postcutoff.com/e/2024-01-09-microsoft-pnnl-battery-electrolyte/","date":"2024-01-09","date_precision":"day","short_title":"Microsoft AI and PNNL screen 32 million candidates to find a solid electrolyte using ~70% less lithium","deck":null,"takeaway":"It is a concrete example of AI compressing the materials search funnel from years to weeks, though the result was a prototype rather than a product.","category":"science","category_label":"Science & math","importance":2,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":3,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Microsoft","Pacific Northwest National Laboratory"]},{"id":"2023-12-20-ai-new-antibiotic-structural-class","url":"https://postcutoff.com/e/2023-12-20-ai-new-antibiotic-structural-class/","date":"2023-12-20","date_precision":"day","short_title":"Explainable deep learning discovers a new structural class of antibiotics against MRSA","deck":null,"takeaway":"New structural classes of antibiotics are rarely discovered.","category":"science","category_label":"Science & math","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":2,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["MIT","Broad Institute"]},{"id":"2023-12-20-coscientist-autonomous-chemistry","url":"https://postcutoff.com/e/2023-12-20-coscientist-autonomous-chemistry/","date":"2023-12-20","date_precision":"day","short_title":"Coscientist: a GPT-4 agent plans and runs real chemistry experiments from plain-English prompts","deck":null,"takeaway":"It was the first peer-reviewed LLM agent operating a physical lab, a precursor of 2026's AI-run labs.","category":"science","category_label":"Science & math","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":2,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Carnegie Mellon University"]},{"id":"2023-12-14-funsearch-cap-sets","url":"https://postcutoff.com/e/2023-12-14-funsearch-cap-sets/","date":"2023-12-14","date_precision":"day","short_title":"FunSearch: an LLM finds new cap-set constructions, the first LLM discovery in open maths","deck":null,"takeaway":"It was the direct ancestor of AlphaEvolve and showed that LLMs' mistakes don't matter when outputs can be automatically checked.","category":"science","category_label":"Science & math","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":3,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google DeepMind","University of Wisconsin–Madison"]},{"id":"2023-12-11-mixtral","url":"https://postcutoff.com/e/2023-12-11-mixtral/","date":"2023-12-11","date_precision":"day","short_title":"Mistral AI releases Mixtral 8x7B, an open mixture-of-experts model","deck":null,"takeaway":"Popularized mixture-of-experts in open models (later used by DeepSeek-V3, Llama 4, Qwen) and established Europe's leading AI startup.","category":"open-source","category_label":"Open source","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Mistral AI"]},{"id":"2023-12-06-gemini-1","url":"https://postcutoff.com/e/2023-12-06-gemini-1/","date":"2023-12-06","date_precision":"day","short_title":"Google DeepMind launches Gemini 1.0","deck":null,"takeaway":"Google's main answer to GPT-4, beginning a Gemini line that reached the frontier with Gemini 2.5 and 3.","category":"model-release","category_label":"Model releases","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google DeepMind","Google"]},{"id":"2023-11-29-gnome-millions-of-materials","url":"https://postcutoff.com/e/2023-11-29-gnome-millions-of-materials/","date":"2023-11-29","date_precision":"day","short_title":"GNoME predicts 2.2 million new crystals, 380,000 stable, but novelty and usefulness are disputed","deck":null,"takeaway":"It is the largest AI materials-prediction effort, and a leading example of the gap between computational \"discovery\" and a useful new material.","category":"science","category_label":"Science & math","importance":4,"confidence":"high","status":{"key":"disputed","labels":["Disputed"]},"sources":3,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google DeepMind","Lawrence Berkeley National Laboratory"]},{"id":"2023-11-29-a-lab-autonomous-synthesis-dispute","url":"https://postcutoff.com/e/2023-11-29-a-lab-autonomous-synthesis-dispute/","date":"2023-11-29","date_precision":"day","short_title":"Berkeley's A-Lab claims 41 new materials from autonomous synthesis","deck":"After critiques Nature corrects it to 36 'inorganic' (not 'novel') materials","takeaway":"It is the clearest case study of overclaiming in AI-driven science, and of how human expert scrutiny corrected it.","category":"science","category_label":"Science & math","importance":3,"confidence":"high","status":{"key":"disputed","labels":["Disputed"]},"sources":3,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Lawrence Berkeley National Laboratory"]},{"id":"2023-11-17-openai-board-crisis","url":"https://postcutoff.com/e/2023-11-17-openai-board-crisis/","date":"2023-11-17","date_precision":"day","short_title":"OpenAI's board fires and then reinstates Sam Altman","deck":null,"takeaway":"Exposed the fragility of non-profit oversight of frontier labs and preceded OpenAI's restructuring toward a for-profit entity.","category":"business","category_label":"Business","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":3,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["OpenAI"]},{"id":"2023-11-14-graphcast-weather","url":"https://postcutoff.com/e/2023-11-14-graphcast-weather/","date":"2023-11-14","date_precision":"day","short_title":"GraphCast: ML weather model beats the world's best physics-based 10-day forecast on 90% of targets","deck":null,"takeaway":"It triggered the rapid move of AI weather models into operational forecasting worldwide.","category":"science","category_label":"Science & math","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":3,"official":3,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google DeepMind"]},{"id":"2023-11-01-bletchley-ai-safety-summit","url":"https://postcutoff.com/e/2023-11-01-bletchley-ai-safety-summit/","date":"2023-11-01","date_precision":"day","short_title":"Bletchley Park AI Safety Summit and the Bletchley Declaration","deck":null,"takeaway":"First intergovernmental agreement on frontier AI risk, and it created the network of national AI safety institutes.","category":"policy-safety","category_label":"Policy & safety","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["UK Government"]},{"id":"2023-10-30-us-executive-order-14110","url":"https://postcutoff.com/e/2023-10-30-us-executive-order-14110/","date":"2023-10-30","date_precision":"day","short_title":"US Executive Order 14110 on safe, secure and trustworthy AI","deck":null,"takeaway":"The most comprehensive US government action on AI at the time; its revocation in 2025 marked a sharp US policy turn toward deregulation.","category":"policy-safety","category_label":"Policy & safety","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["The White House"]},{"id":"2023-09-19-alphamissense","url":"https://postcutoff.com/e/2023-09-19-alphamissense/","date":"2023-09-19","date_precision":"day","short_title":"AlphaMissense classifies 89% of all 71 million possible human missense mutations","deck":null,"takeaway":"It gives clinicians a first-pass interpretation for millions of variants they otherwise could not assess.","category":"science","category_label":"Science & math","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google DeepMind"]},{"id":"2023-07-18-llama-2","url":"https://postcutoff.com/e/2023-07-18-llama-2/","date":"2023-07-18","date_precision":"day","short_title":"Meta releases Llama 2 with a commercial-use license","deck":null,"takeaway":"Legitimized open-weights LLMs in industry and intensified the open vs. closed AI policy debate.","category":"open-source","category_label":"Open source","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Meta","Microsoft"]},{"id":"2023-07-11-rfdiffusion-protein-design","url":"https://postcutoff.com/e/2023-07-11-rfdiffusion-protein-design/","date":"2023-07-11","date_precision":"day","short_title":"RFdiffusion: diffusion models design new proteins that work in the lab","deck":null,"takeaway":"It became the workhorse of AI protein design, underlying AI antivenoms, antibodies and enzymes.","category":"science","category_label":"Science & math","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":3,"official":3,"filed":"2026-09-29","updated":"2026-09-29","orgs":["University of Washington Institute for Protein Design"]},{"id":"2023-07-11-claude-2","url":"https://postcutoff.com/e/2023-07-11-claude-2/","date":"2023-07-11","date_precision":"day","short_title":"Anthropic releases Claude 2 with public claude.ai access","deck":null,"takeaway":"Established Claude as a mainstream alternative to ChatGPT and pushed long-context as a competitive feature.","category":"model-release","category_label":"Model releases","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Anthropic"]},{"id":"2023-06-07-alphadev-sorting","url":"https://postcutoff.com/e/2023-06-07-alphadev-sorting/","date":"2023-06-07","date_precision":"day","short_title":"AlphaDev discovers faster small-sort routines, merged into LLVM's C++ standard library","deck":null,"takeaway":"It was AI-discovered code shipping in core infrastructure, though experts argued about how novel the discovery really was.","category":"science","category_label":"Science & math","importance":3,"confidence":"high","status":{"key":"disputed","labels":["Disputed"]},"sources":3,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google DeepMind"]},{"id":"2023-05-30-cais-statement-ai-risk","url":"https://postcutoff.com/e/2023-05-30-cais-statement-ai-risk/","date":"2023-05-30","date_precision":"day","short_title":"Leading AI scientists sign the one-sentence statement on AI extinction risk","deck":null,"takeaway":"Brought catastrophic AI risk into mainstream policy discourse, paving the way for the Bletchley summit and AI safety institutes.","category":"policy-safety","category_label":"Policy & safety","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":2,"official":2,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Center for AI Safety"]},{"id":"2023-05-30-nvidia-1-trillion","url":"https://postcutoff.com/e/2023-05-30-nvidia-1-trillion/","date":"2023-05-30","date_precision":"day","short_title":"NVIDIA becomes the first chipmaker worth $1 trillion","deck":null,"takeaway":"NVIDIA's valuation became the market's barometer for the AI boom and of the scale of capital flowing into compute.","category":"business","category_label":"Business","importance":3,"confidence":"medium","status":{"key":"partly","labels":["Partly confirmed"]},"sources":2,"official":0,"filed":"2026-09-29","updated":"2026-09-29","orgs":["NVIDIA"]},{"id":"2023-05-25-abaucin-ai-antibiotic","url":"https://postcutoff.com/e/2023-05-25-abaucin-ai-antibiotic/","date":"2023-05-25","date_precision":"day","short_title":"AI finds abaucin, a narrow-spectrum antibiotic against the superbug Acinetobacter baumannii","deck":null,"takeaway":"It showed that AI could find narrow-spectrum antibiotics, which spare the microbiome and slow resistance.","category":"science","category_label":"Science & math","importance":3,"confidence":"high","status":{"key":"confirmed","labels":["Result confirmed"]},"sources":2,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["McMaster University","MIT"]},{"id":"2023-05-01-hinton-leaves-google","url":"https://postcutoff.com/e/2023-05-01-hinton-leaves-google/","date":"2023-05-01","date_precision":"day","short_title":"Geoffrey Hinton leaves Google so he can speak freely about AI risks","deck":null,"takeaway":"When one of the field's founders publicly switched to warning about it, AI x-risk moved into the mainstream.","category":"policy-safety","category_label":"Policy & safety","importance":4,"confidence":"high","status":{"key":"confirmed","labels":["Confirmed"]},"sources":5,"official":1,"filed":"2026-09-29","updated":"2026-09-29","orgs":["Google"]}]}